Lymphoma is a type of cancer that affects the lymphatic system, a key component of the immune system responsible for fighting infections and maintaining fluid balance. When lymphocytes (a type of white blood cell) grow uncontrollably, they form tumors in the lymph nodes and other parts of the body, leading to lymphoma.
If you’ve been searching for what is the difference between Hodgkin’s and non-Hodgkin’s cancer, you’re not alone. Both Hodgkin lymphoma and non-Hodgkin lymphoma (NHL) share some similarities but differ in causes, cell types, and treatment options. Understanding these differences is crucial for early detection, diagnosis, and treatment.
At Immunity Therapy Center (ITC), we offer alternative and holistic cancer therapies to support patients through their lymphoma cancer journey. In this article, we’ll explore Hodgkin vs Non-Hodgkin Lymphoma, key symptoms, risk factors, and holistic treatments.
What is Hodgkin’s Lymphoma?
Hodgkin’s lymphoma (HL) is a specific type of lymphoma that originates in B-cell lymphocytes and is distinguished by the presence of Reed-Sternberg cells—large, abnormal cells that can be identified under a microscope.1 This is one of the main factors in determining the difference between Hodgkin’s and non-Hodgkin’s lymphoma.
Understanding what causes lymphoma can help identify potential risk factors, though the exact cause of HL remains unclear. HL is less common than NHL and typically starts in the lymph nodes of the neck, chest, or underarms. It often spreads in a predictable manner through the lymphatic system, making it easier to detect and treat early.
Signs and Symptoms of Hodgkin’s Lymphoma
The signs and symptoms of Hodgkin lymphoma may be mild at first but can gradually become more noticeable as the disease progresses. Common symptoms include:
- Swollen lymph nodes in the neck, armpits, or groin
- Unexplained weight loss and persistent fatigue
- Frequent fevers, night sweats, and chills
- Severe itching or skin rashes
- Pain in the lymph nodes after consuming alcohol
Diagnosing Hodgkin’s Lymphoma
Are you wondering about the best ways to check for lymphoma? Doctors may recommend various tests to diagnose Hodgkin lymphoma.
- Physical examination to check for swollen lymph nodes
- Blood tests to detect abnormalities in white blood cells
- Imaging tests (CT scans, MRI, PET scans) to assess lymph node involvement
- Lymph node biopsy to confirm the presence of Reed-Sternberg cells
With early diagnosis and treatment, Hodgkin’s lymphoma has a high survival rate, making timely detection crucial.2
What is Non-Hodgkin’s Lymphoma?
Non-Hodgkin lymphoma (NHL) refers to a group of cancers that originate in the lymphocytes but do not involve Reed-Sternberg cells.3 NHL is more common than Hodgkin lymphoma and includes a wider range of subtypes, each with different growth patterns, affected cell types, and prognosis.
NHL can start in the B cells or T cells and may develop in various areas of the lymphatic system, such as the lymph nodes, spleen, bone marrow, and other organs. Unlike Hodgkin lymphoma, NHL does not follow a predictable pattern, making early detection more challenging.
Signs and Symptoms of Non-Hodgkin’s Lymphoma
Since NHL has multiple subtypes, symptoms can vary, but some of the most common include:
- Painless swelling of lymph nodes in the neck, armpits, or groin
- Unexplained weight loss and persistent fatigue
- Fever, night sweats, and chills
- Abdominal pain or swelling (if the spleen or liver is involved)
- Shortness of breath or chest pain (if lymphoma spreads to the chest)
Diagnosing Non-Hodgkin’s Lymphoma
Because NHL includes multiple subtypes, diagnosing it requires several tests, such as:
- Lymph node biopsy to examine cancer cells
- Blood tests to evaluate lymphocyte levels and infection markers
- Bone marrow biopsy to determine cancer spread
- Imaging tests (CT, MRI, or PET scans) to assess tumor location and size
Since NHL varies in aggressiveness, some cases progress slowly (indolent NHL), while others grow rapidly (aggressive NHL). The prognosis and treatment plan depend on the lymphoma subtype and stage.
Key Differences Between Hodgkin’s and Non-Hodgkin’s Lymphoma
When comparing Hodgkin non-Hodgkin lymphoma, several key differences set them apart. These differences in cell type, spread, and prognosis are crucial in determining what is the difference between Hodgkin’s and non-Hodgkin’s lymphoma.
| Feature | Hodgkin’s Lymphoma | Non-Hodgkin’s Lymphoma |
| Cell Type | Presence of Reed-Sternberg cells | No Reed-Sternberg cells may be B-cell or T-cell lymphoma |
| Growth & Spread | Spreads in an orderly pattern through the lymphatic system | Can spread unpredictably |
| Common Symptoms | Swollen lymph nodes, night sweats, weight loss, fever, pain after drinking alcohol | Swollen lymph nodes, fever, weight loss, fatigue, shortness of breath |
| Age Group Affected | More common in young adults (15-40) and older adults | Can occur at any age, risk increases with age |
| Survival Rate | High survival rate with early detection and treatment | Varies depending on subtype and stage |
But is lymphoma hereditary? Lymphoma is not typically hereditary, but having a family history of lymphoma may slightly increase an individual’s risk. While most cases of Hodgkin’s lymphoma and non-Hodgkin’s lymphoma occur sporadically, some genetic mutations can be inherited and may contribute to a higher susceptibility.
Holistic Therapies for Lymphoma: Exploring Alternative Treatments
At Immunity Therapy Center (ITC), we believe in a comprehensive approach to cancer care that goes beyond conventional treatments. We take an alternative approach to cancer care, prioritizing non-toxic, patient-focused therapies that strengthen the immune system, reduce inflammation, and promote natural healing. Our goal is to empower patients with effective, non-invasive treatment options that align with their healing journey.
Here are some of the holistic therapies that you may check out:
Oxygen Therapy
Oxygen plays a crucial role in cellular health and immune function. Oxygen therapy increases oxygen levels in the body, which helps create an environment where cancer cells struggle to thrive. By improving circulation and oxygenation, this therapy supports healthy tissue and enhances the body’s ability to fight lymphoma naturally.
Hyperthermia Therapy
Hyperthermia therapy uses controlled heat to target cancer cells while preserving surrounding healthy tissues. This temperature-based therapy has been studied for its potential to weaken cancer cells and enhance the effectiveness of the immune system. By increasing blood flow and stimulating immune responses, hyperthermia therapy may provide additional support for patients undergoing lymphoma treatment.
Immunotherapy
The immune system plays a vital role in defending the body against diseases, including Hodgkin lymphoma and non-Hodgkin lymphoma (NHL). Immunotherapy focuses on enhancing the body’s natural defense mechanisms to recognize and eliminate abnormal lymphoma cells. By stimulating the immune response, this therapy supports long-term wellness while minimizing toxicity to healthy cells.
Detoxification Therapies
A healthy immune system functions best when the body is free from toxins and harmful substances. Detox therapies help remove environmental toxins, heavy metals, and oxidative stress, all of which can contribute to cancer development and progression. ITC offers personalized detoxification programs that focus on cleansing and strengthening the body’s natural defenses.
Nutritional Therapy
Diet plays a crucial role in lymphoma prevention and management. A balanced, anti-inflammatory diet rich in antioxidants, vitamins, and minerals helps support the immune system and combat cellular damage. At ITC, we guide patients through nutrition therapies to ensure they are receiving the essential nutrients needed for optimal healing and recovery.
Making Informed Healthcare Decisions
Understanding what is the difference between non-Hodgkin’s and Hodgkin’s lymphoma cancer can help patients and their families make informed healthcare decisions. While both forms of lymphoma affect the lymphatic system, they differ in cell types, progression, and treatment approaches.
At Immunity Therapy Center, we provide holistic, patient-focused care designed to enhance immune function, promote healing, and support overall well-being. If you or a loved one has been diagnosed with lymphoma or if you’re interested in exploring holistic cancer care, our team is here to help. Contact us today to learn more about our personalized, holistic lymphoma treatment options and take control of your health journey.
Written By: Dr. Pablo Orozco
Dr. Pablo Orozco is a Board Certified Medical Doctor from Universidad Autónoma de Baja California.
Dr. Orozco has been a treating physician at the Immunity Therapy Center for more than 3 years providing daily on site patient care. He works with patients on a daily basis and guides them through the treatment process. Dr. Orozco’s passion for Alternative Cancer Treatments along with his commitment to patient care is key to insure that our patients have the best experience and results possible.
Sources:
- National Library of Medicine. Hodgkin Lymphoma. https://www.ncbi.nlm.nih.gov/books/NBK499969/
- Medical News Today. What to know about lymphoma. https://www.medicalnewstoday.com/articles/146136
- Cancer Research UK. What is non-Hodgkin lymphoma? https://www.cancerresearchuk.org/about-cancer/non-hodgkin-lymphoma/about
At Immunity Therapy Center, our goal is to provide objective, updated, and research-based information on all health-related topics. This article is based on scientific research and/or other scientific articles. All information has been fact-checked and reviewed by Dr. Carlos Bautista, a Board Certified Medical Doctor at Immunity Therapy Center. All information published on the site must undergo an extensive review process to ensure accuracy. This article contains trusted sources with all references hyperlinked for the reader's visibility.