What Causes Lymphoma Cancer?

Lymphoma cancer is a type of blood cancer that originates in the lymphatic system, a vital part of the body’s immune defense. It develops when lymphocytes—a type of white blood cell—begin to grow and multiply uncontrollably, forming cancerous tumors in the lymph nodes, bone marrow, and other organs.

But what causes lymphoma cancer in the first place? While the exact cause remains unclear, genetic mutations, immune system dysfunction, viral infections, and environmental factors all play a role in increasing the risk of developing lymphoma. Understanding these risk factors is key to early detection and preventing lymphoma before it progresses.

Genetic and Environmental Factors Contributing to Lymphoma

Although anyone can develop lymphoma, certain genetic and environmental factors can significantly increase risk.¹ These factors don’t guarantee a lymphoma diagnosis, but they may contribute to the mutations that trigger abnormal cell growth in the lymphatic system.

Genetic Predisposition and DNA Changes

Is lymphoma hereditary? One of the leading risk factors for lymphoma cancer is genetic mutations that alter the way lymphocytes function. These mutations may occur naturally over time or be inherited from family members.

• Inherited genetic conditions: While lymphoma itself isn’t directly inherited, individuals with a family history of Hodgkin lymphoma or non-Hodgkin lymphoma may be at higher risk. Is lymphoma hereditary? The answer is complex—while most cases occur sporadically, genetics can still play a role in susceptibility.
• DNA mutations: Changes in DNA can cause B cells or T cells—two types of lymphocytes—to replicate uncontrollably. These changes may occur due to age, environmental exposure, or immune system dysfunction.
• Autoimmune disorders: Conditions like rheumatoid arthritis or lupus can trigger chronic inflammation and increase the risk of developing lymphoma.²

Environmental Risk Factors

How do you get lymphoma from the environment? Exposure to certain chemicals and pollutants has been linked to an increased risk of lymphoma.

• Pesticides and herbicides: Studies have found a link between long-term exposure to agricultural chemicals and higher rates of non-Hodgkin lymphoma (NHL).
• Industrial solvents and toxins: Working in industries that involve benzene, dioxins, or other toxic substances may also contribute to developing lymphoma.
• Radiation exposure: Those who have undergone radiation therapy for other cancers may face a higher risk of lymphoma cancer later in life.

While genetics and environmental exposure are major contributors, other immune-related and lifestyle factors also play a role.

The Role of the Immune System in Lymphoma Development

The immune system is responsible for fighting infections, eliminating abnormal cells, and preventing disease. However, when the immune system becomes compromised, it may fail to detect cancer cells, allowing them to grow unchecked.

How Immune Dysfunction Contributes to Lymphoma

A weakened immune system is one of the most significant risk factors for lymphoma cancer. People with suppressed immune function—whether due to illness, medical treatments, or genetic conditions—are more likely to develop Hodgkin lymphoma or non-Hodgkin lymphoma.

• HIV/AIDS: Individuals with HIV/AIDS are at a much higher risk of lymphoma because the virus attacks the T cells, weakening immune function.
• Organ transplant recipients: Patients who receive organ transplants must take immunosuppressive medications, which increase the risk of developing lymphoma.
• Chronic infections: Ongoing infections can lead to chronic inflammation, which may trigger abnormal cell growth in the lymphatic system.

The Connection Between a Weak Immune System and Lymphoma

The lymphatic system plays a key role in filtering out toxins, bacteria, and damaged cells. When lymphocytes stop functioning properly, they may accumulate and form tumors in the lymph nodes, spleen, or bone marrow.

Here’s how the different types of lymphoma can start in your lymphatic system:

• Hodgkin lymphoma often starts in one group of lymph nodes before spreading to others.
• Non-Hodgkin lymphoma can occur anywhere in the body where lymphatic tissue is present.

This is why strengthening the immune system is crucial to preventing and supporting lymphoma treatments.t Is also important to understand the difference between Hodgkin’s and non-Hodgkin’s cancer to better recognize risk factors and treatment options.

Other Potential Causes of Lymphoma

What are the other causes of lymphoma? In addition to genetics, environmental exposure, and immune dysfunction, several other risk factors may contribute to lymphoma cancer.

Infections Linked to Lymphoma

Certain viral and bacterial infections have been associated with a higher risk of developing Hodgkin lymphoma and non-Hodgkin lymphoma.

• Epstein-Barr virus (EBV): This virus causes mononucleosis and has been linked to Hodgkin lymphoma and some B-cell lymphomas.³
• Hepatitis C: Long-term hepatitis infections can trigger chronic immune activation, leading to a higher risk of lymphoma.
• H. Pylori bacteria: This stomach infection has been linked to gastric lymphoma, a type of non-Hodgkin lymphoma that forms in the stomach lining.

Lifestyle Factors That May Play a Role

While there is no definitive lifestyle cause of lymphoma, certain habits can increase the risk of developing lymphoma.

• Smoking: Although smoking is more commonly linked to lung cancer, research suggests it may also contribute to lymphoma by increasing inflammation in the lymphatic system.
• Diet and nutrition: Diets high in processed foods and low in antioxidants may contribute to chronic inflammation, weakening the immune response.
• Obesity: Being overweight has been linked to a higher risk of non-Hodgkin lymphoma, likely due to increased inflammation and hormonal imbalances.

While lifestyle choices may not be a direct cause of lymphoma, they can influence immune health, making it easier for cancer cells to grow and spread.

Alternative Approaches to Preventing Lymphoma

While some risk factors for lymphoma—such as genetics and past infections—cannot be changed, there are ways to strengthen the immune system and support overall health to lower the risk of developing lymphoma. At Immunity Therapy Center (ITC), we focus on alternative cancer treatments that empower the body to heal naturally and help prevent disease progression.

Boosting the Immune System with Holistic Therapies

A strong immune system plays a vital role in preventing abnormal cell growth in the lymphatic system. Since lymphoma cancer often develops when lymphocytes become damaged or dysfunctional, reinforcing immune defenses is one of the most effective preventative measures.

At ITC, we focus on natural, non-invasive therapies that support immune health and enhance the body’s ability to fight cancer cells. Our holistic approach includes:

• Oxygen Therapy: In oxygen therapy, the increased oxygen levels create an environment where cancer cells struggle to survive, while also promoting cellular repair and immune function.
• Hyperthermia Therapy: By using controlled heat, hyperthermia therapy stimulates immune activity and helps target abnormal lymphoma cells while preserving healthy tissue.
• Nutritional Support: ITC offers gerson therapy with a customized anti-inflammatory diet, including fruits, vegetables, and herbal supplements, which can help reduce chronic inflammation and improve immune function.

These therapies help support the body’s natural ability to identify and eliminate harmful cells before they multiply, offering a proactive approach to lymphoma prevention.

The Role of Regular Screening in Early Detection

Since lymphoma symptoms—such as swollen lymph nodes, fatigue, or night sweats—can often be mistaken for other illnesses, early detection is key to improving lymphoma outcomes. Knowing how to check for lymphoma through routine health assessments can make a significant difference.

At ITC, we emphasize the importance of regular health screenings and listening to your body. If you experience persistent symptoms, consulting with a healthcare provider can help determine the next steps for diagnosis and treatment.

Some common diagnostic tests to check for lymphoma cancer include:

• Biopsy: A tissue sample is taken from a swollen lymph node to check for cancerous cells.
• Blood tests: These help assess immune function and detect abnormalities in white blood cell counts.
• Imaging scans (CT, MRI, PET scans): These scans identify potential tumors and assess whether the cancer has spread.

Since lymphoma cancer can develop in both Hodgkin’s and non-Hodgkin’s forms, getting an accurate diagnosis ensures the best treatment plan moving forward.

Strengthening the Body Against Lymphoma Cancer

Understanding what causes lymphoma cancer can help you take proactive steps to protect your health. While genetics, environmental exposure, and immune dysfunction are key risk factors, lifestyle changes and alternative therapies can support immune function and lower the likelihood of developing lymphoma.

At Immunity Therapy Center (ITC), we specialize in holistic therapies designed to help patients take control of their health journey. Our non-invasive treatments focus on strengthening the immune system, reducing inflammation, and improving overall well-being—all of which are essential for lymphoma prevention and supporting cancer recovery.

To learn more about alternative approaches to lymphoma care, visit ITC and explore how our innovative therapies can help you achieve optimal health.

 

Written By: Dr. David Alvarez

Dr. David Alvarez is a Board Certified Medical Doctor from Universidad Xochicalco and Certified by the American Heart Association (Advanced Cardiovascular Life Support).

Dr. Alvarez has been collaborating with Dr. Bautista as an Assistant Medical Director at the Immunity Therapy Center for over 6 years. He provides daily on site patient care and participates on the medical board on research and development of patient treatment plans and programs. Dr. Alvarez is a knowledgeable and compassionate Doctor committed to helping patients get to where they want to be health wise through a more holistic and comprehensive approach.

 

Sources:

1. Medical News Today. Is lymphoma a genetic condition? https://www.medicalnewstoday.com/articles/is-lymphoma-genetic
2. American Cancer Society. Non-Hodgkin Lymphoma Risk Factors. https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/risk-factors.html
3. National Library of Medicine. How Epstein Barr Virus Causes Lymphomas. https://pmc.ncbi.nlm.nih.gov/articles/PMC11599019/

Dr. Carlos Bautista is a Board Certified Medical Doctor. He received his Medical Degree from Universidad Autónoma de Baja California and has more than 20 years of experience working with Alternative Medicine to treat cancer, autoimmune diseases, chronic degenerative diseases, and infectious diseases. He opened Immunity Therapy Center in 2007 with the goal of providing the highest quality medical care for more than 5,000 patients.

At Immunity Therapy Center, our goal is to provide objective, updated, and research-based information on all health-related topics. This article is based on scientific research and/or other scientific articles. All information has been fact-checked and reviewed by Dr. Carlos Bautista, a Board Certified Medical Doctor at Immunity Therapy Center. All information published on the site must undergo an extensive review process to ensure accuracy. This article contains trusted sources with all references hyperlinked for the reader's visibility.